Episode 96

GLP-1 Medications Uncovered: Semaglutide, Tirzepatide & the Hidden Effects Providers Must Know

Published on: 13th November, 2025

In this episode of Beauty & The Brain, Dr. Chris Croley and NP Jerry Drinkard break down the most in-demand medications in modern weight loss and metabolic health: GLP-1 medications, including semaglutide, tirzepatide, Wegovy, Ozempic, and Zepbound.

Together, they explore how these drugs actually work, who they help most, and the unexpected ways they impact the body far beyond weight loss.

Inside this episode, you’ll learn:

  • How GLP-1 medications regulate appetite, cravings, inflammation & blood sugar
  • The shift from compounded semaglutide to manufacturer-direct options
  • Why some patients experience fertility changes, libido shifts, hair thinning & mood effects
  • The rise of microdosing GLP-1s to reduce nausea, fatigue & muscle loss
  • Anti-aging and neuroprotective research emerging around GLP-1 therapy
  • Why rapid weight loss accelerates facial aging—and how Sculptra can help preserve structure
  • How exercise, protein intake & body composition affect long-term results

Whether you're a patient using GLP-1 therapy or a provider prescribing it, this episode offers evidence-based insight, real patient experiences, and practical solutions for navigating side effects and treatment longevity.

Follow Beauty & The Brain for weekly conversations on aesthetic medicine, regenerative wellness, weight-loss science, and the future of medical aesthetics.

GLP-1, semaglutide, tirzepatide, Wegovy, Ozempic, Zepbound, medical weight loss, aesthetic medicine, Sculptra, microdosing GLP-1

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About the Podcast

Beauty & The Brain®
A Deep Dive into Medical Aesthetics
Welcome to Beauty & The Brain, the podcast where we take a deep dive into the fascinating world of medical aesthetics! I'm Dr. Chris Croley, and I'm joined by my co-host Jerry Drinkard, a board-certified Family Nurse Practitioner. Together, we co-own Skin & Tonic, a medical spa that's passionate about providing the latest and greatest treatments to help our clients look and feel their best.

We started this podcast out of our love for medical aesthetics and our desire to share our knowledge and insights with others. Every week, we'll be discussing new trends, sharing our thoughts on controversial topics, and keeping you up to date on the latest technology in the industry. But we won't just be talking to ourselves! We're excited to bring in experts and industry leaders to share their perspectives and insights with our listeners.

Our goal is to provide a podcast that's authentic, informative, and genuinely helpful for anyone who's interested in beauty and wellness. Whether you're a beauty enthusiast or a medical professional, we hope you'll tune in every week to learn something new and join us on this journey of discovery.

So, if you're ready to dive into the world of medical aesthetics, join us on Beauty & The Brain, and let's explore this fascinating industry together!